Cornea and External Diseases
The cornea is the clear, outer layer covering the front of the eye. It acts as a barrier to protect the eye from foreign objects, helps with vision by focusing light, and filters ultraviolet rays that enter the eye.
The cornea can usually heal itself after scratches or minor injuries. However, the cornea and other external eye structures require medical treatment for more serious injuries, allergies, inflammation, infections, corneal dystrophies, and a wide range of other conditions.

Blepharitis: Blepharitis is one of the most common ocular conditions characterized by inflammation, scaling, reddening, and crusting of the eyelid. This condition may also cause burning, itching, or a grainy sensation when introducing foreign objects or substances to the eye. Although blepharitis is not sight-threatening, it can lead to permanent alterations of the eyelid margin. The overall etiology is a result of bacteria and inflammation from congested meibomian oil glands at the base of each eyelash. ¹
Conjunctivitis: Sometimes called “pink eye,” conjunctivitis means inflammation of the outer covering of the white part of the eye, the conjunctiva. It can result from allergy, irritation, viral infection, or bacterial infection. Each type has its own symptoms and signs. If an eye is red for more than a day or two, has a lot of discharge, or is painful or blurry, the patient should be examined by an ophthalmologist.
Corneal dystrophies: These are a group of conditions of the cornea. Some are mild changes that a doctor can see only with a microscope and which don’t cause any problems. Others, however, can lead to corneal haze or opacities and can affect vision. Many corneal dystrophies run in families.
Dry Eye Syndrome or Dysfunctional Tear Syndrome: As people age, the eye loses some of its ability to make tears. Because the eye is designed to work “under water,” inadequate tears can cause blurry vision as well as irritation. This condition is often treated by using artificial tears, drops, and ointments. There are also medications available to help the eye to make more of its own tear or to supplement and lubricate the cornea.
Epiphora or excessive tearing: This is a condition in which the eye tears too much. It can be caused by too much tear production, by inadequate drainage of the tears from the eyes, or by malposition of the lower eyelids. Generally, inadequate drainage and malposition of the lids can be surgically corrected.
Fuchs’ corneal dystrophy: This condition affects the innermost layer of the cornea, the endothelium, causing it to lose the ability to keep fluid from soaking into the cornea. If the endothelium needs to be replaced, then surgery with either DSAEK or DMEK is performed.
Herpes keratitis: This inflammation and infection of the cornea can be caused by either the herpes simplex virus, which causes the common fever blisters, or by the herpes zoster virus (same as the chicken pox virus) that causes shingles. Both can result in scarring of the cornea and inflammation inside the eye. Patients with herpes simplex infection might experience fever blisters, red eye, blurry vision, and light sensitivity. Patients with herpes zoster might experience mid-face breakouts with shingles and considerable pain. Patients should seek care promptly.
Keratitis: Inflammation or infection of the cornea. There are many causes, but symptoms generally include sensitivity to light, blurry vision, and irritation. This generally needs evaluation and treatment.
Keratoconus: In some people, the cornea is weak and tends to lose its shape easily and over time, becoming cone-shaped and resulting in blurry, out-of-focus vision.
Photokeratitis: Photokeratitis is an inflammation of the cornea caused by exposure to light. Exposure can be from welding, too much sun exposure, or overexposure to UV light, such as from a tanning booth. It generally heals completely but can be quite uncomfortable.
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Pterygium: Is a wing-like fleshy mass usually noted at the nasal side of the eye, This is usually secondary to irritation, drying of the eye and exposure to sunlight. Condition is usually not visually threatening except if the mass is big causing astigmatism and or extends up to the pupil which blocks vision.
Symptoms affecting the cornea include:
• Eye pain
• Sensitivity to light
• Blurry, reduced, or distorted vision
• Excessing tearing
• Redness, itching, burning, stinging, or inflammation in the eye
• Discharge from the eye
• Headache, nausea, fatigue
• Feeling of having something in the eye
• Poor night vision
• Cloudy cornea
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